Rethinking treatment for nervous system disorders
Empowering patients to live on their own terms
Who We Are
At its core, Eliem is motivated by the promise of helping people live happier, more fulfilling lives. The Eliem team channels its experience, energy and passion for improving patients’ quality of life by developing life-changing novel therapies for neuronal excitability disorders based on clinically validated mechanisms of action.

Our Approach: Optimizing Treatments for Neuronal Excitability Disorders
Tens of millions of people suffer from central and peripheral nervous system disorders, where an imbalance between excitation and inhibition has disrupted the homeostasis in affected neuronal networks. These disorders include a range of common conditions such as chronic pain, depression, epilepsy and anxiety. Currently available treatments for these conditions often fail to provide adequate control or relief, and they are often poorly tolerated, leaving people unable to live life on their own terms.
Developing improved treatments for patients requires a pragmatic and diligent approach. Equal parts rigorous and agile, the experienced Eliem team strives to make treatments that are more effective, safer and better tolerated than currently available treatments. Leveraging clinically validated mechanisms of action, we are moving steadily and efficiently to develop novel therapeutics for neuronal excitability disorders that deliver enhanced outcomes for patients.
Our Pipeline
Our two lead drug candidates have clinically validated mechanisms of action for neurological diseases and have demonstrated encouraging clinical and preclinical results. We are developing ETX-810 for chronic pain and ETX-155 for major depressive disorder, perimenopausal depression and focal onset seizures. These compounds are designed to dramatically improve on the limitations of existing therapies with the potential to be best-in-class for these conditions with high unmet clinical needs.
Our Experienced Team
The team’s combined expertise in neurological research, clinical development, commercialization and company building are critical for delivering on the promise of bringing innovative therapies to market to provide relief and hope for the millions of patients affected by neurological conditions.










Mark received his M.D. from University of Antwerp, Belgium, Ph.D. (Dr. Med.) in clinical pharmacology from Humboldt University in Berlin, Germany and MBA from University of Michigan.


















News
Eliem Therapeutics Reports First Quarter Financial and Business Highlights
Eliem Provides Update on ETX-810 and ETX-155 Clinical Programs
By Bob Azelby
More restrictive opioid prescribing guidelines were put in place in a rightful effort to stop a devastating crisis. But this sudden and dramatic change negatively impacted chronic pain patients who were managing their pain through prescription opioids given few other effective options.
Careers
We are always looking to grow our team and believe it takes teamwork, trust and tenacity to deliver on the promise of helping patients live happier, more fulfilling lives. If this sounds like you, please indicate which position you are interested in and contact us at Careers US or Careers UK.
We’d love to connect.
Location: Cambridge UK
About Eliem:
Eliem Therapeutics is a clinical-stage biotechnology company developing medicines for patients with neurologic diseases. Our pipeline has two clinical stage compounds in conditions focused on pain and other neurological conditions. The company continues to grow its preclinical pipeline in neurology.
Eliem launched in 2018 and completed its initial public offering in 2021. The company has locations in the Greater Seattle Area, WA and Cambridge, UK. For further information visit our website: https://eliemtx.com
About this role:
We are looking for an experienced scientific leader to join our biology team, to work closely with the Head of Biology, the Chief Scientific Officer (CSO) and our project teams to provide independent leadership of scientific strategies and oversee the biology research on our projects. You will ideally have a broad scientific background, including molecular biology techniques, biochemical, cell based and translational assays development and knowledge of cutting-edge new technologies within drug discovery. You will be able to demonstrate a strong track record of independent scientific leadership, as evidenced by delivery of numerous project milestones, publications and/or co-inventorship on patent applications.
Key Responsibilities:
- Working in close collaboration with the head of biology, CSO and project teams to provide independent leadership of scientific strategies, by designing and coordinating work plans, providing reviews and interpretation of data, actively managing project resources and finances, and using strategic decision making and creative problem solving to achieve project goals
- Oversee the biology research on projects as required by working across matrix teams within the organisation and with specific vendors or external consultants on project teams, to support basic and applied research across all company projects
- Identification and management of appropriately selected qualified vendors, to enable high quality data generation, data management and statistical activities to biology study report finalisation, in accordance with both corporate and regulatory standards
- Co-ordinate research activities across projects as required in accordance with corporate quality processes for vendor identification & selection and support the preparation and review of scientific proposals
- Apply biology, drug development and operational knowledge to translate research ideas into high quality desired endpoints in translational and clinical studies where applicable
- Oversight and management of CROs to whom responsibilities have been delegated, to including review of research protocols & modifications, data management and statistical analysis
- Responsibility for the biology contributions and quality control of key documents including protocols, investigator brochures and regulatory submissions & updates
- With a focus on continuous improvement, keep up to date on scientific research & technological advances and industry trends to enable recommendations on new research or technological opportunities
- Monitor and keep up to date on the activities of competitors in the key areas of Eliem’s research activities to identify aspects of improvement and differentiation
Key Requirements:
Essential:
- Educated to degree level in a scientific subject with significant drug discovery experience or a PhD with several years’ experience in a CRO or Pharma/biotech environment, preferably companies that have undergone rapid expansion or merged through approaches of integration
- Scientific leadership experience with a significant track record of success in leading and managing scientific teams. Proven extensive experience as a biology discipline or project leader across a range of disease indications
- Significant experience of working in collaboration with academic and commercial organisations (CRO’s and Biotechnology companies)
- Ability to work in a fast-moving organization and demonstrates a high level of personal merit and performance at a senior level
- A dynamic, can-do attitude and a flexible approach to problem solving
- Excellent leadership, communication, and interpersonal skills with the ability to communicate effectively with staff at all levels and different cultures with an ability to inspire others
- Significant experience of working in collaboration with academic and commercial organisations (CRO’s and Biotechnology companies)
Desirable:
- Demonstrate a capacity to lead and develop initiatives within a strategic framework
- General awareness of MHRA, EMA and FDA standards for drug discovery projects
- Experience of preparing and reviewing documents for IND submissions
- A good working knowledge of software packages commonly used such as MS Office, Sharepoint, Studytracker, Concur and analysis packages such as GraphPad Prism, Dotmatics is also desirable although training will be provided
We offer our employees competitive salary and benefits, including pension (9% employer contribution), life assurance, income protection, private medical insurance and share options.
To apply please send your CV and a covering letter to CareersUK@eliemtx.com, quoting job reference E22/04
Location: Cambridge UK
About Eliem:
Eliem Therapeutics is a clinical-stage biotechnology company developing medicines for patients with neurologic diseases. Our pipeline has two clinical stage compounds in conditions focused on pain and other neurological conditions. The company continues to grow its preclinical pipeline in neurology.
Eliem launched in 2018 and completed its initial public offering in 2021. The company has locations in the Greater Seattle Area, WA and Cambridge, UK. For further information visit our website: https://eliemtx.com
About this role:
We are looking for an experienced scientific leader to join our biology team, to work closely with the Head of Biology, the Chief Scientific Officer (CSO) and our project teams to provide independent leadership of scientific strategies and oversee the biology research on our projects. You will ideally have a broad scientific background, including molecular biology techniques, biochemical, cell based and translational assays development and knowledge of cutting-edge new technologies within drug discovery. You will be able to demonstrate a strong track record of independent scientific leadership, as evidenced by delivery of numerous project milestones, publications and/or co-inventorship on patent applications.
Key Responsibilities:
- Working in close collaboration with the head of biology, CSO and project teams to provide independent leadership of scientific strategies, by designing and coordinating work plans, providing reviews and interpretation of data, actively managing project resources and finances, and using strategic decision making and creative problem solving to achieve project goals
- Oversee the biology research on projects as required by working across matrix teams within the organisation and with specific vendors or external consultants on project teams, to support basic and applied research across all company projects
- Identification and management of appropriately selected qualified vendors, to enable high quality data generation, data management and statistical activities to biology study report finalisation, in accordance with both corporate and regulatory standards
- Co-ordinate research activities across projects as required in accordance with corporate quality processes for vendor identification & selection and support the preparation and review of scientific proposals
- Apply biology, drug development and operational knowledge to translate research ideas into high quality desired endpoints in translational and clinical studies where applicable
- Oversight and management of CROs to whom responsibilities have been delegated, to including review of research protocols & modifications, data management and statistical analysis
- Responsibility for the biology contributions and quality control of key documents including protocols, investigator brochures and regulatory submissions & updates
- With a focus on continuous improvement, keep up to date on scientific research & technological advances and industry trends to enable recommendations on new research or technological opportunities
- Monitor and keep up to date on the activities of competitors in the key areas of Eliem’s research activities to identify aspects of improvement and differentiation
Key Requirements:
Essential:
- Educated to degree level in a scientific subject with significant drug discovery experience or a PhD with several years’ experience in a CRO or Pharma/biotech environment, preferably companies that have undergone rapid expansion or merged through approaches of integration
- Scientific leadership experience with a significant track record of success in leading and managing scientific teams. Proven extensive experience as a biology discipline or project leader across a range of disease indications
- Significant experience of working in collaboration with academic and commercial organisations (CRO’s and Biotechnology companies)
- Ability to work in a fast-moving organization and demonstrates a high level of personal merit and performance at a senior level
- A dynamic, can-do attitude and a flexible approach to problem solving
- Excellent leadership, communication, and interpersonal skills with the ability to communicate effectively with staff at all levels and different cultures with an ability to inspire others
- Significant experience of working in collaboration with academic and commercial organisations (CRO’s and Biotechnology companies)
Desirable:
- Demonstrate a capacity to lead and develop initiatives within a strategic framework
- General awareness of MHRA, EMA and FDA standards for drug discovery projects
- Experience of preparing and reviewing documents for IND submissions
- A good working knowledge of software packages commonly used such as MS Office, Sharepoint, Studytracker, Concur and analysis packages such as GraphPad Prism, Dotmatics is also desirable although training will be provided
We offer our employees competitive salary and benefits, including pension (9% employer contribution), life assurance, income protection, private medical insurance and share options.
To apply please send your CV and a covering letter to CareersUK@eliemtx.com, quoting job reference E22/04
Contact Us
23515 NE Novelty Hill Road, Suite B221 #125
Redmond, WA 98053
Eliem Therapeutics (UK) Ltd: Reg. 11893311
3rd Floor, 1 Ashley Road
Altrincham, Cheshire WA14 2DT